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Buffalo Bills vs. Indianapolis Colts prediction, odds, +1500 best bet for today’s NFL game (11/10/2024)

The Buffalo Bills will square off with the Indianapolis Colts in Week 10 of the NFL season at Lucas Oil Stadium on Sunday. Kickoff is at 1 p.m. EST, with our detailed betting preview below providing you an update on our early Bills at Colts prediction from the beginning of the week.
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Note: This preview includes Dimers’ best bets and predicted scoreline for the Buffalo Bills vs. Indianapolis Colts. To unlock Dimers’ full suite of data-driven betting insights, which includes daily props, trends, and parlays, sign up for Dimers Pro with promo code SYRACUSE10, which will save you 10% off your first subscription payment.
Explore the interactive widget below to discover the current spread, total, and moneyline betting odds and probabilities for the Bills-Colts matchup at Lucas Oil Stadium.
This prediction and best bet for Sunday’s NFL matchup between the Bills and Colts is from Dimers.com, a trusted source for sports betting predictions.
Check out all the important details on today’s game, as well as the best odds sourced from the top sportsbooks in the country.
The key information you need before the Bills vs. Colts NFL game.
The latest and best odds for the NFL game between the Bills and Colts.
The odds and lines featured here are the best available from selected sports betting site at the time of publication and are subject to change.
Utilizing state-of-the-art data analysis and advanced algorithms, the experts at Dimers have executed 10,000 simulations of Sunday’s Bills vs. Colts game.
According to Dimers’ independent predictive analytics model, the Bills are more likely to beat the Colts at Lucas Oil Stadium. This prediction is based on the model giving the Bills a 63% chance of winning the game.
Furthermore, Dimers predicts that the Bills (-3.5) have a 52% chance of covering the spread, while the 47.5-point over/under has a 52% chance of staying under.
These predictions and probabilities are accurate at the time of publication but are subject to potential changes.
Despite not featuring in our top three most likely scorers for the Bills in the list below, our recommended bet here is Ty Johnson anytime TD Scorer (+1500).
The secondary running back has scored in three of nine games already this season, and is now presenting value to do so again according to the experts at Dimers.
The current available odds only imply a 6.3% chance of Johnson scoring, meaning we have it down as twice as likely to happen as the bookmakers do!
Dimers’ projected final score for the Buffalo vs. Indianapolis game on Sunday has the Bills winning 25-21.
This expert prediction is based on each team’s average score following 10,000 game simulations, offering a glimpse into the potential outcome.
NFL prop bets are an exciting way to wager on Sunday’s game without necessarily betting on its outcome.
This article features the most likely first and anytime touchdown scorers for the Bills and Colts, as well as projected player stats.
Get ready for Sunday’s game between the Bills and Colts in Week 10 of the National Football League season at Lucas Oil Stadium, which is scheduled to start at 1 p.m. EST. We emphasize that all of the NFL predictions and NFL best bets in this article are based on 10,000 data-driven simulations of the Bills vs. Colts matchup, and they are correct at the time of publication to help you make better decisions when placing bets at online sportsbooks.
It is important to gamble responsibly and consult reliable sources for the latest and most accurate information when making online betting choices.

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